Protein name:
Growth hormone receptor (GH receptor) ;
Alternative:
Somatotropin receptor ;
Organism:
Pig (Sus scrofa).
General Annotation
Sub Unit:
On growth hormone (GH) binding, forms homodimers and binds JAK2 via a box 1-containing domain (By similarity). Binding to SOCS3 inhibits JAK2 activation, binding to CIS and SOCS2 inhibits STAT5 activation.
Function:
The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling.
Subcellular Location:
Cell membrane
Single-pass type I membrane protein
On growth hormone binding, GHR is ubiquitinated, internalized, down-regulated and transported into a degradative or non-degradative pathway.
Protein Attributes:
50:
MDLWQLLLTL | AVAGSSDAFS | GSEATPAVLV | RASQSLQRVH | PGLETNSSGK |
100:
PKFTKCRSPE | LETFSCHWTD | GVRHGLQSPG | SIQLFYIRRS | TQEWTQEWKE |
150:
CPDYVSAGEN | SCYFNSSYTS | IWIPYCIKLT | SNGGTVDQKC | FSVEEIVQPD |
200:
PPIGLNWTLL | NISLTGIHAD | IQVRWEPPPN | ADVQKGWIVL | EYELQYKEVN |
250:
ETQWKMMDPV | LSTSVPVYSL | RLDKEYEVRV | RSRQRNSEKY | GEFSEVLYVT |
300:
LPQMSPFACE | EDFRFPWFLI | IIFGIFGLTV | ILFLLIFSKQ | QRIKMLILPP |
350:
VPVPKIKGID | PDLLKEGKLE | EVNTILAIHD | NYKHEFYSDD | SWVEFIELDI |
400:
DDPDEKTEGS | DTDRLLNNDH | EKSLTILGAK | EDDSGRTSCY | EPDILETDFN |
450:
ANDVCDGTAE | VAQPQRLKGE | ADLLCLDQKN | QNNSPSNDAA | PATQQPSVIL |
500:
AEENKPRPLI | ISGTDSTHQT | AHTQLSNPSS | LANIDFYAQV | SDITPAGSVV |
550:
LSPGQKNKAG | ISQCDMHLEV | VSPCPANFIM | DNAYFCEADA | KKCIAMAPHV |
600:
EVESRLAPSF | NQEDIYITTE | SLTTTAGRSA | TAECAPSSEM | PVPDYTSIHI |
638:
VQSPQGLVLN | ATALPLPDKE | FLSSCGYVST | DQLNKIMP
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Pig
Mouse
Chicken
Dog
Rat
Rabbit
Bovine
ELISA Kit for Pig GH receptor
ELISA Kit for Pig GH receptor
ELISA Kit for Pig GH receptor
ELISA Kit for Pig GH receptor
ELISA Kit for Pig GH receptor
ELISA Kit for Pig GH receptor
ELISA Kit for Pig GH receptor
ELISA Kit for Pig GH receptor
CLIA Kit for Pig GH receptor
CLIA Kit for Pig GH receptor
CLIA Kit for Pig GH receptor
CLIA Kit for Pig GH receptor
CLIA Kit for Pig GH receptor
CLIA Kit for Pig GH receptor
CLIA Kit for Pig GH receptor
CLIA Kit for Pig GH receptor
Polyclonal Antibody for Pig GH receptor
Polyclonal Antibody for Pig GH receptor
Polyclonal Antibody for Pig GH receptor
Polyclonal Antibody for Pig GH receptor
Polyclonal Antibody for Pig GH receptor
Polyclonal Antibody for Pig GH receptor
Polyclonal Antibody for Pig GH receptor
Polyclonal Antibody for Pig GH receptor
Monoclonal Antibody for Pig GH receptor
Monoclonal Antibody for Pig GH receptor
Monoclonal Antibody for Pig GH receptor
Monoclonal Antibody for Pig GH receptor
Monoclonal Antibody for Pig GH receptor
Monoclonal Antibody for Pig GH receptor
Monoclonal Antibody for Pig GH receptor
Monoclonal Antibody for Pig GH receptor
Protein for Pig GH receptor
Protein for Pig GH receptor
Protein for Pig GH receptor
Protein for Pig GH receptor
Protein for Pig GH receptor
Protein for Pig GH receptor
Protein for Pig GH receptor
Protein for Pig GH receptor
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
Landrace X Yorkshire .
tissue :
Liver .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION;STAT5 ACTIVATION;MUTAGENESIS OF TYR-332; TYR-337; TYR-390; TYR-487; TYR-534; TYR-566; TYR-595 AND TYR-627