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Index > Protein center > GHR(Gene name) > Pig
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  • GHR (Gene name),
  • Growth hormone receptor (Protein name ),  GHR_PIG from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    GHR;
    Protein name:
    Growth hormone receptor(GH receptor);
    Alternative:
    Somatotropin receptor;
    Organism:
    Pig (Sus scrofa). 
    General Annotation
    Sub Unit:
    On growth hormone (GH) binding, forms homodimers and binds JAK2 via a box 1-containing domain (By similarity). Binding to SOCS3 inhibits JAK2 activation, binding to CIS and SOCS2 inhibits STAT5 activation.
    Function:
    The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling.
    Subcellular Location:
    Cell membrane Single-pass type I membrane protein On growth hormone binding, GHR is ubiquitinated, internalized, down-regulated and transported into a degradative or non-degradative pathway.
    Protein Attributes:
    Sequence length:
    638
    Sequence:
    50:
    MDLWQLLLTL | AVAGSSDAFS | GSEATPAVLV | RASQSLQRVH | PGLETNSSGK | 
    100:
    PKFTKCRSPE | LETFSCHWTD | GVRHGLQSPG | SIQLFYIRRS | TQEWTQEWKE | 
    150:
    CPDYVSAGEN | SCYFNSSYTS | IWIPYCIKLT | SNGGTVDQKC | FSVEEIVQPD | 
    200:
    PPIGLNWTLL | NISLTGIHAD | IQVRWEPPPN | ADVQKGWIVL | EYELQYKEVN | 
    250:
    ETQWKMMDPV | LSTSVPVYSL | RLDKEYEVRV | RSRQRNSEKY | GEFSEVLYVT | 
    300:
    LPQMSPFACE | EDFRFPWFLI | IIFGIFGLTV | ILFLLIFSKQ | QRIKMLILPP | 
    350:
    VPVPKIKGID | PDLLKEGKLE | EVNTILAIHD | NYKHEFYSDD | SWVEFIELDI | 
    400:
    DDPDEKTEGS | DTDRLLNNDH | EKSLTILGAK | EDDSGRTSCY | EPDILETDFN | 
    450:
    ANDVCDGTAE | VAQPQRLKGE | ADLLCLDQKN | QNNSPSNDAA | PATQQPSVIL | 
    500:
    AEENKPRPLI | ISGTDSTHQT | AHTQLSNPSS | LANIDFYAQV | SDITPAGSVV | 
    550:
    LSPGQKNKAG | ISQCDMHLEV | VSPCPANFIM | DNAYFCEADA | KKCIAMAPHV | 
    600:
    EVESRLAPSF | NQEDIYITTE | SLTTTAGRSA | TAECAPSSEM | PVPDYTSIHI | 
    638:
    VQSPQGLVLN | ATALPLPDKE | FLSSCGYVST | DQLNKIMP
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    SMR:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Pig GH receptor
    Cat.:
    E1036h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Pig GH receptor
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    E1036p
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Pig GH receptor
    Cat.:
    E1036m
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    Packing:
    96T
    ELISA Kit for Pig GH receptor
    Cat.:
    E1036c
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    96T
    ELISA Kit for Pig GH receptor
    Cat.:
    E1036d
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    96T
    ELISA Kit for Pig GH receptor
    Cat.:
    E1036r
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    Packing:
    96T
    ELISA Kit for Pig GH receptor
    MSDS:
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    ELISA Kit for Pig GH receptor
    Cat.:
    E1036b
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    Packing:
    96T
    CLIA Kit for Pig GH receptor
    Cat.:
    U1036d
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Pig GH receptor
    Cat.:
    U1036r
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Pig GH receptor
    Cat.:
    U1036c
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Pig GH receptor
    Cat.:
    U1036p
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Pig GH receptor
    Cat.:
    U1036m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Pig GH receptor
    Cat.:
    U1036b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Pig GH receptor
    Cat.:
    U1036h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Pig GH receptor
    MSDS:
    Please sign in first.
    Polyclonal Antibody for Pig GH receptor
    Cat.:
    P1036Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Pig GH receptor
    Cat.:
    P1036Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Pig GH receptor
    Polyclonal Antibody for Pig GH receptor
    Cat.:
    P1036Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Pig GH receptor
    Polyclonal Antibody for Pig GH receptor
    Polyclonal Antibody for Pig GH receptor
    Polyclonal Antibody for Pig GH receptor
    Monoclonal Antibody for Pig GH receptor
    Monoclonal Antibody for Pig GH receptor
    Monoclonal Antibody for Pig GH receptor
    Monoclonal Antibody for Pig GH receptor
    Monoclonal Antibody for Pig GH receptor
    Monoclonal Antibody for Pig GH receptor
    Monoclonal Antibody for Pig GH receptor
    Monoclonal Antibody for Pig GH receptor
    Protein for Pig GH receptor
    Cat.:
    R1036h
    Price:
    Please sign in first.
    Packing:
    1mg
    Purity:
    >90%
    Protein for Pig GH receptor
    Protein for Pig GH receptor
    Protein for Pig GH receptor
    Protein for Pig GH receptor
    Protein for Pig GH receptor
    Protein for Pig GH receptor
    Protein for Pig GH receptor

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    References
    1. 1.
      "Porcine growth hormone receptor cDNA sequence."
      Cioffi J.A. , Wang X. , Kopchick J.J.
      Nucleic Acids Res.18:6451-6451(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Landrace X Yorkshire.
      tissue: Liver.
    2. 2.
      "Identification of tyrosine residues in the intracellular domain of the growth hormone receptor required for transcriptional signaling and Stat5 activation."
      Hansen L.H. , Wang X. , Kopchick J.J. , Bouchelouche P. , Nielsen J.H. , Galsgaard E.D. , Billestrup N.
      J. Biol. Chem.271:12669-12673(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION;STAT5 ACTIVATION;MUTAGENESIS OF TYR-332; TYR-337; TYR-390; TYR-487; TYR-534; TYR-566; TYR-595 AND TYR-627
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